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Low dose cyproterone acetate (progestin with anti-andorgenic activity) results in similar suppression of serum androgens for transgender women compared with higher doses. This approach may be safer, although more work is needed

https://www.jsm.jsexmed.org/article/S1743-6095(21)00431-8/fulltext?fbclid=IwAR3gDQPSy4QkT_QH-V-Z23RmT9j3qO7nvXNazS5ajbu8ZGfJGzqJOjKyEsc