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Cystitis associated with COVID-19

Scientists from the United States conducted a study of urine samples and proved that high levels of pro-inflammatory cytokines cause COVID-19 associated cystitis.The 2019 coronavirus infection (COVID-19) caused by the SARS-CoV-2 virus can cause a wide range of symptoms. These include fever, cough, fatigue, and unexpected symptoms, including loss of taste, puffy eyelids, and discharge from the eyes, as well as gastrointestinal symptoms including loss of appetite, nausea, vomiting, and diarrhea.Recently, patients with confirmed COVID-19 were found to have an increase in the frequency of urination, as well as the development of severe urinary symptoms - more than 13 episodes of urination per day and more than 4 episodes of nocturia. Some patients also reported pain or discomfort associated with urination. Scientists have named these symptoms of COVID-19 associated cystitis (CAC).Since the severity of COVID-19 is associated with inflammation and increased levels of inflammatory cytokines, American scientists hypothesized that ASC may occur in COVID-19 and be caused by an increase in pro-inflammatory cytokines that are secreted into urine and / or expressed in the bladder wall. For this, urine samples were collected from patients with coronavirus infection, including patients with SAS, in which the expression of inflammatory cytokines was examined.The results of the study confirmed the high level of pro-inflammatory cytokines in the urine of patients with coronavirus. This allowed scientists to draw several conclusions about what doctors need to know about COVID-19 associated cystitis; first-appearance symptoms of urination should be included in the complex of symptoms associated with COVID-19; and that coronavirus infection can lead to bladder dysfunction.